2024
Direct and Indirect Control of Rho-Dependent Transcription Termination by the Escherichia coli lysC Riboswitch. 2022
SHAPE-enabled fragment-based ligand discovery for RNA.
Site-specific photolabile roadblocks for the study of transcription elongation in biologically complex systems. 2021
Monitoring RNA dynamics in native transcriptional complexes.
Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection.
A structural intermediate pre-organizes the add adenine riboswitch for ligand recognition. 2020
Riboswitch regulation mechanisms: RNA, metabolites and regulatory proteins. 2019
Role of a hairpin-stabilized pause in the Escherichia coli thiC riboswitch function.
Unprecedented tunability of riboswitch structure and regulatory function by sub-millimolar variations in physiological Mg2. 2018
The yeast telomerase recruitment module requires a specific RNA architecture.
Maestro of regulation: Riboswitches orchestrate gene expression at the levels of translation, transcription and mRNA decay. 2017
Ligand recognition and helical stacking formation are intimately linked in the SAM-I riboswitch regulatory mechanism.
Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation.
Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation. 2016
Biophysical Approaches to Bacterial Gene Regulation by Riboswitches.
The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate.
Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes. 2015
Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile.
A kissing loop is important for btuB riboswitch ligand sensing and regulatory control.
Role of lysine binding residues in the global folding of the lysC riboswitch.
Single-Molecule Approaches for the Characterization of Riboswitch Folding Mechanisms.
Probing of Nascent Riboswitch Transcripts.
Functional Studies of DNA-Protein Interactions Using FRET Techniques. 2014
RNA conformational changes analyzed by comparative gel electrophoresis.
Fluorescence tools to investigate riboswitch structural dynamics.
Using sm-FRET and denaturants to reveal folding landscapes. 2013
A new telomerase RNA element that is critical for telomere elongation.
Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assay.
Regulatory RNAs and target mRNA decay in prokaryotes.
Single-molecule denaturation of riboswitches.
Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog. 2012
Dual-acting riboswitch control of translation initiation and mRNA decay.
Folding of the SAM-I riboswitch: A tale with a twist. 2011
Constitutive regulatory activity of an evolutionary-excluded riboswitch variant.
New insights into riboswitch regulation mechanisms.
Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms.
Folding of the lysine riboswitch: importance of peripheral elements for transcriptional regulation. 2010
Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways.
Therapeutic applications of ribozymes and riboswitches.
Small RNA-mediated regulation at the level of transcript stability.
Riboswitch structure: an internal residue mimicking the purine ligand. 2009
Functional studies of DNA-protein interactions using FRET techniques.
Molecular Basis of RNA-Mediated Gene Regulation on the Adenine Riboswitch by Single-Molecule Approaches.
Application of Fluorescence Measurements for Characterization of Riboswitch-Ligand Interactions.
Riboswitches: Ancient and Promising Genetic Regulators. 2008
Natural Functional Nucleic Acids: Ribozymes and Riboswitches.
Folding of the SAM Aptamer is Determined by the Formation of a K-turn-dependent Pseudoknot. 2007
Ligand recognition determinants of guanine riboswitches.
A loop-loop interaction and a K-turn motif located in the lysine aptamer domain are important for the riboswitch gene regulation control.
Core requirements of the adenine riboswitch aptamer for ligand binding.
2006
Folding of the adenine riboswitch.
Le ribor�gulateur ad�nine: Un nouveau mode de r�gulation g�n�tique.
2002
The global structure of the VS ribozyme.
Functional group requirements in the probable active site of the VS ribozyme.
Folding and catalysis by the VS ribozyme.
The structure and active site of the Varkud satellite ribozyme.
2001
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction.
The A730 loop is an important component of the active site of the VS ribozyme.
2000
Nucleotides -1 to -4 of hepatitis delta ribozyme substrate increase the specificity of ribozyme cleavage.
1999
Presence of a coordinated metal ion in a trans-acting antigenomic delta ribozyme.
Mutational analysis of the antigenomic trans-acting delta ribozyme: the alterations of the middle nucleotides located on the P1 stem.
The viroid and viroid-like RNA database.
1998
Kinetic analysis of delta ribozyme cleavage.
Identification of a Crohn's disease specific transcript with potential as a diagnostic marker.
The viroid and viroid-like RNA database.
1997
Update of the viroid and viroid-like sequence database: addition of a hepatitis delta virus RNA section.
1996
Compilation and analysis of viroid and viroid-like RNA sequences.
1995
Intra- and intermolecular nonenzymatic ligations occur within transcripts derived from the peach latent mosaic viroid.
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